The GraphQL mutation OCDevManageApplicationSubmissionMetadataAssetsMutation fails with error code 1891859 when submitting app metadata updates. This error occurs because the metadata configuration blocks the app from being available on all supported Quest devices, resulting in no devices being purchasable. The issue is specifically related to the app submission metadata assets workflow and requires that at least one device be unblocked under Purchase-Blocked Devices in the Specs section of App Metadata settings to resolve.